15 New Messages
Digest #19736
Messages
Thu Apr 18, 2013 6:46 pm (PDT) . Posted by:
"/Ghozan"
nimbrung dikit copas dari yg kemarin :
ada 3 alasan dokter cenderung 'abusive' dlm peresepannya:
- lack of convidence/ kurang 'PD"
- patient pressure=> yg sering saya temukan kasusnya buanyak - kan
tinggal gesek/bayar asuransi...zzzzzzzz.
- company pressure
*Company Pressure*
Bisa datang dari fihak manajemen RS, kenapa penting utk menulis surat
'cinta' agar supaya dokter2 yg baik ini lebih banyak dan atau minimal
dipertahankan.
Atau justru sebaliknya, karena RS masih tergolong baru 5tahun, masih
perlu balik modal, yg ditekan dokternya, akhirnya dokter yg mestinya ga
perlu kasih obat 'pura' kasih vitamin, atau yg gak perlu pemeriksaan
penunjang, karena alat mahal biar balik modal perlu pemeriksan penunjang.
Alhasil dokter meresepkan 'abusive', yg kuat akan melawan arus,
pahit2nya di depak dengan cara halus.....ini ri'il.
Bisa juga datang dari pabrik obat, ini namanya 'industrio medical
complex' ini bukan hal baru- sudah menjadi rahasia umum berpuluh tahun
tidak akan pernah hilang.
Salam pembelajar
ghz
ada 3 alasan dokter cenderung 'abusive&#
- lack of convidence/ kurang 'PD"
- patient pressure=> yg sering saya temukan kasusnya buanyak - kan
tinggal gesek/bayar asuransi...zzzzzzzz
- company pressure
*Company Pressure*
Bisa datang dari fihak manajemen RS, kenapa penting utk menulis surat
'cinta&#
dipertahankan.
Atau justru sebaliknya, karena RS masih tergolong baru 5tahun, masih
perlu balik modal, yg ditekan dokternya, akhirnya dokter yg mestinya ga
perlu kasih obat 'pura' kasih vitamin, atau yg gak perlu pemeriksaan
penunjang, karena alat mahal biar balik modal perlu pemeriksan penunjang.
Alhasil dokter meresepkan 'abusive&#
pahit2nya di depak dengan cara halus.....ini ri'il.
Bisa juga datang dari pabrik obat, ini namanya 'industrio medical
complex' ini bukan hal baru- sudah menjadi rahasia umum berpuluh tahun
tidak akan pernah hilang.
Salam pembelajar
ghz
Thu Apr 18, 2013 6:49 pm (PDT) . Posted by:
ni.nugroho
Pagi all,
Nyumbang link dulu sambil baca2 sendiri biar paham:
http://www.nlm.nih.gov/medlineplus/ency/patientinstructions/000512.htm
http://emedicine.medscape.com/article/261137-overview
Happy reading, nanti klo udh baca saya posting lagi ya...
Salam,
Rini
Sent from my BlackBerry® smartphone from Sinyal Bagus XL, Nyambung Teruuusss...!
Nyumbang link dulu sambil baca2 sendiri biar paham:
http://www.nlm.
http://emedicine.
Happy reading, nanti klo udh baca saya posting lagi ya...
Salam,
Rini
Sent from my BlackBerry® smartphone from Sinyal Bagus XL, Nyambung Teruuusss...
Thu Apr 18, 2013 6:58 pm (PDT) . Posted by:
"nadya lonianto" nadyalonianto
Dear mb joice,
Sharing aja ya...
Saya dulu juga PKD,pecahnya jam 4 subuh,lahiran jam 7 malam,means udah 15 jam an ya *mrinding kalo inget
Tapi anak saya ngga di beri AB sih...
Maaf ngga bantu :(
Nadya
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Sharing aja ya...
Saya dulu juga PKD,pecahnya jam 4 subuh,lahiran jam 7 malam,means udah 15 jam an ya *mrinding kalo inget
Tapi anak saya ngga di beri AB sih...
Maaf ngga bantu :(
Nadya
Sent from my BlackBerry®
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Thu Apr 18, 2013 7:26 pm (PDT) . Posted by:
"Agustin, Nina(JKT-HRS)"
Dear Mba Joice,
Sharing juga yah...
Waktu itu saya juga PKD, pecahnya jam 23.30 dan lahirnya besok jam 23.00 tapi tidak diberi AB.
Terimakasih,
Nina
Sharing juga yah...
Waktu itu saya juga PKD, pecahnya jam 23.30 dan lahirnya besok jam 23.00 tapi tidak diberi AB.
Terimakasih,
Nina
Thu Apr 18, 2013 7:27 pm (PDT) . Posted by:
rika_elfira
Dear mba'joice,
Anak ke2 saya jg KPD...kalo mau tau ttg antibiotik dan KPD bisa browsing rupture of membranes and antibiotik...
saya total dari pecah ketuban ke lahir itu 9jam tapi ga dikasih AB...bayi jg ga dikasih AB
Dari baca sekilas link2nya (belum sempet baca thoroughly)...terapi AB biasanya diberikan pada ibu setelah sekian jam (kalo ga salah 18 jam) dr pecah ketuban belum lahir jg untuk mengurangi infeksi pada bayi dan ibu...
Management of ruptured membranes at term:
www.medscape.com/viewarticle/4944127
Antibiotics for prelabour rupture of membranes at or near term:
http://apps.who.int/rhl/reviews/CD001807.pdf
Thx®ards,
@rikaelfira
(bundanya alya-3yo & arka-7mo)
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Anak ke2 saya jg KPD...kalo mau tau ttg antibiotik dan KPD bisa browsing rupture of membranes and antibiotik..
saya total dari pecah ketuban ke lahir itu 9jam tapi ga dikasih AB...bayi jg ga dikasih AB
Dari baca sekilas link2nya (belum sempet baca thoroughly).
Management of ruptured membranes at term:
www.medscape.
Antibiotics for prelabour rupture of membranes at or near term:
http://apps.
Thx®ards,
@rikaelfira
(bundanya alya-3yo & arka-7mo)
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Thu Apr 18, 2013 8:08 pm (PDT) . Posted by:
"/Ghozan"
On 4/19/2013 9:29 AM, rika.corner@gmail.com wrote:
> Dari baca sekilas link2nya (belum sempet baca thoroughly)...terapi AB biasanya diberikan pada ibu setelah sekian jam (kalo ga salah 18 jam) dr pecah ketuban belum lahir jg untuk mengurangi infeksi pada bayi dan ibu...
=> biar lebih jelas saya bantu copas disini
saya quote sedikit saja biar ga pening bacanya :)
Rating Scheme for the Strength of the Recommendations
Based on the highest level of evidence found in the data,
recommendations are provided and graded according to the following
categories:
*Level A* — Recommendations are based on good and consistent scientific
evidence.
*Level B* — Recommendations are based on limited or inconsistent
scientific evidence.
*Level C* — Recommendations are based primarily on consensus and expert
opinion.
Cost Analysis
Guideline developers reviewed published cost analyses.
Method of Guideline Validation
Internal Peer Review
Description of Method of Guideline Validation
Practice Bulletins are validated by two internal clinical review panels
composed of practicing obstetrician-gynecologists generalists and
sub-specialists. The final guidelines are also reviewed and approved by
the American College of Obstetricians and Gynecologists (ACOG) Executive
Board.
Back to top <http://guideline.gov/content.aspx?id=34024#top >
Recommendations
Major Recommendations
The grades of evidence (I-III) and levels of recommendation (A-C) are
defined at the end of the "Major Recommendations" field.
*The following recommendations are based on good and consistent
scientific evidence (Level A)*:
* Antimicrobial prophylaxis is recommended for all cesarean deliveries
unless the patient is already receiving appropriate antibiotics
(e.g., for chorioamnionitis) and that prophylaxis should be
administered within 60 minutes before the start of the cesarean
delivery.
* For cesarean delivery prophylaxis, a single dose of a targeted
antibiotic, such as a first-generation cephalosporin, is the
first-line antibiotic of choice, unless significant drug allergies
are present.
* Antibiotic prophylaxis is indicated for patients with preterm
premature rupture of membranes (PROM) to prolong the latency period
between membrane rupture and delivery.
* Antibiotic prophylaxis should not be used for pregnancy prolongation
in women with preterm labor and intact membranes. This
recommendation is distinct from recommendations for antibiotic use
for preterm PROM and group B streptococci (GBS) carrier status.
*The following recommendations are based on limited or inconsistent
scientific evidence (Level B)*:
* For women with a history of a significant penicillin or
cephalosporin allergy (anaphylaxis, angioedema, respiratory
distress, or urticaria), a single-dose combination of clindamycin
with an aminoglycoside is a reasonable alternative choice for
cesarean delivery prophylaxis.
* Infective endocarditis prophylaxis is no longer recommended for
either vaginal or cesarean delivery in the absence of infection
except possibly for the small subset of patients at highest
potential risk of adverse cardiac outcomes who are undergoing
vaginal delivery.
*The following recommendations are based primarily on consensus and
expert opinion (Level C)*:
* Evidence is insufficient to recommend antibiotic prophylaxis for
either prophylactic or emergency cerclage.
* In obese patients (body mass index [BMI] greater than 30) undergoing
cesarean delivery, consideration should be given to using a higher
dose of preoperative antibiotics for surgical prophylaxis.
*Definitions*:
*Grades of Evidence*
*I*: Evidence obtained from at least one properly designed randomized
controlled trial.
*II-1*: Evidence obtained from well-designed controlled trials without
randomization.
*II-2*: Evidence obtained from well-designed cohort or case–control
analytic studies, preferably from more than one center or research group.
*II-3*: Evidence obtained from multiple time series with or without the
intervention. Dramatic results in uncontrolled experiments also could be
regarded as this type of evidence.
*III*: Opinions of respected authorities, based on clinical experience,
descriptive studies, or reports of expert committees.
*Levels of Recommendations*
*Level A* — Recommendations are based on good and consistent scientific
evidence.
*Level B* — Recommendations are based on limited or inconsistent
scientific evidence.
*Level C* — Recommendations are based primarily on consensus and expert
opinion.
Clinical Algorithm(s)
None provided
Back to top <http://guideline.gov/content.aspx?id=34024#top >
Evidence Supporting the Recommendations
Type of Evidence Supporting the Recommendations
The type of supporting evidence is identified and graded for each
recommendation (see the "Major Recommendations" field).
Back to top <http://guideline.gov/content.aspx?id=34024#top >
Benefits/Harms of Implementing the Guideline Recommendations
Potential Benefits
Appropriate use of prophylactic antibiotics in labor and delivery
Potential Harms
* Changes have been reported in resistance patterns of isolated
strains of /Escherichia coli/ in newborns, particularly after
maternal antibiotic administration.
* Risks of antibiotic administration include allergic reactions or
anaphylaxis. Skin reactions to cephalosporins include urticaria,
rash, and pruritus. A case of anaphylaxis to penicillin after
administration for group B streptococci (GBS) prophylaxis has been
reported, and there are reports of exfoliative dermatitis and severe
immune hemolytic anemia associated with cephalosporin therapy.
selengkapnya :
http://guideline.gov/content.aspx?id=34024
[Non-text portions of this message have been removed]
> Dari baca sekilas link2nya (belum sempet baca thoroughly).
=> biar lebih jelas saya bantu copas disini
saya quote sedikit saja biar ga pening bacanya :)
Rating Scheme for the Strength of the Recommendations
Based on the highest level of evidence found in the data,
recommendations are provided and graded according to the following
categories:
*Level A* — Recommendations are based on good and consistent scientific
evidence.
*Level B* — Recommendations are based on limited or inconsistent
scientific evidence.
*Level C* — Recommendations are based primarily on consensus and expert
opinion.
Cost Analysis
Guideline developers reviewed published cost analyses.
Method of Guideline Validation
Internal Peer Review
Description of Method of Guideline Validation
Practice Bulletins are validated by two internal clinical review panels
composed of practicing obstetrician-
sub-specialists. The final guidelines are also reviewed and approved by
the American College of Obstetricians and Gynecologists (ACOG) Executive
Board.
Back to top <http://guideline.
Recommendations
Major Recommendations
The grades of evidence (I-III) and levels of recommendation (A-C) are
defined at the end of the "Major Recommendations&quo
*The following recommendations are based on good and consistent
scientific evidence (Level A)*:
* Antimicrobial prophylaxis is recommended for all cesarean deliveries
unless the patient is already receiving appropriate antibiotics
(e.g., for chorioamnionitis) and that prophylaxis should be
administered within 60 minutes before the start of the cesarean
delivery.
* For cesarean delivery prophylaxis, a single dose of a targeted
antibiotic, such as a first-generation cephalosporin, is the
first-line antibiotic of choice, unless significant drug allergies
are present.
* Antibiotic prophylaxis is indicated for patients with preterm
premature rupture of membranes (PROM) to prolong the latency period
between membrane rupture and delivery.
* Antibiotic prophylaxis should not be used for pregnancy prolongation
in women with preterm labor and intact membranes. This
recommendation is distinct from recommendations for antibiotic use
for preterm PROM and group B streptococci (GBS) carrier status.
*The following recommendations are based on limited or inconsistent
scientific evidence (Level B)*:
* For women with a history of a significant penicillin or
cephalosporin allergy (anaphylaxis, angioedema, respiratory
distress, or urticaria), a single-dose combination of clindamycin
with an aminoglycoside is a reasonable alternative choice for
cesarean delivery prophylaxis.
* Infective endocarditis prophylaxis is no longer recommended for
either vaginal or cesarean delivery in the absence of infection
except possibly for the small subset of patients at highest
potential risk of adverse cardiac outcomes who are undergoing
vaginal delivery.
*The following recommendations are based primarily on consensus and
expert opinion (Level C)*:
* Evidence is insufficient to recommend antibiotic prophylaxis for
either prophylactic or emergency cerclage.
* In obese patients (body mass index [BMI] greater than 30) undergoing
cesarean delivery, consideration should be given to using a higher
dose of preoperative antibiotics for surgical prophylaxis.
*Definitions*
*Grades of Evidence*
*I*: Evidence obtained from at least one properly designed randomized
controlled trial.
*II-1*: Evidence obtained from well-designed controlled trials without
randomization.
*II-2*: Evidence obtained from well-designed cohort or case–control
analytic studies, preferably from more than one center or research group.
*II-3*: Evidence obtained from multiple time series with or without the
intervention. Dramatic results in uncontrolled experiments also could be
regarded as this type of evidence.
*III*: Opinions of respected authorities, based on clinical experience,
descriptive studies, or reports of expert committees.
*Levels of Recommendations*
*Level A* — Recommendations are based on good and consistent scientific
evidence.
*Level B* — Recommendations are based on limited or inconsistent
scientific evidence.
*Level C* — Recommendations are based primarily on consensus and expert
opinion.
Clinical Algorithm(s)
None provided
Back to top <http://guideline.
Evidence Supporting the Recommendations
Type of Evidence Supporting the Recommendations
The type of supporting evidence is identified and graded for each
recommendation (see the "Major Recommendations&quo
Back to top <http://guideline.
Benefits/Harms of Implementing the Guideline Recommendations
Potential Benefits
Appropriate use of prophylactic antibiotics in labor and delivery
Potential Harms
* Changes have been reported in resistance patterns of isolated
strains of /Escherichia coli/ in newborns, particularly after
maternal antibiotic administration.
* Risks of antibiotic administration include allergic reactions or
anaphylaxis. Skin reactions to cephalosporins include urticaria,
rash, and pruritus. A case of anaphylaxis to penicillin after
administration for group B streptococci (GBS) prophylaxis has been
reported, and there are reports of exfoliative dermatitis and severe
immune hemolytic anemia associated with cephalosporin therapy.
selengkapnya :
http://guideline.
[Non-text portions of this message have been removed]
Sent from BlackBerry® on 3
-----Original Message-----
From: marcella.kasih@
Sender: sehat@yahoogroups.
Date: Thu, 18 Apr 2013 19:16:55
To: <sehat@yahoogroups.
Reply-To: sehat@yahoogroups.
Cc: <joiceronalita@
Subject: [sehat] Tolong dibantu - Pemberian garamycin
Jeung Joice, maaf saya posting ke milis barang kali ada yang bisa bantu jawab juga ya.
Sepengetahuan saya, praktek ini memang seperti SOP dibanyak rumah sakit untuk kasus anak pecah ketuban dini. Tujuannya sih salah satu tindakan pencegahan infeksi.
Berhubung saya gak punya pengalaman, file maupun linknya, dan kebetulan gak bisa browsing juga saat ini (dari tadi icon jam udah muncul2, mesti hard reset) jadi gak bisa konfirmasi, tepatnya gimana. Takut salah juga.
Dokters dan Teman2 Sps, tolong dibantu ya.
Rgds,
Marcella
*mpok bawel
------Original Message-----
From: joiceronalita@
To: marcella.kasih@
ReplyTo: joiceronalita@
Subject: Pemberian garamycin
Sent: Apr 19, 2013 1:11 AM
Mlm mba cella,
Boleh minta bantuan advice mba?
Maaf mengganggu, sinyal di rumah sakit tidak memmungkinkan utk browsing.
Sy baru lahiran putri saya Kyrie, pukul 16.20 sore, bb 2850 secara normal dengan induksi krn sdh pecah ketuban jam 6 pagi ketika bangun pagi, nah tadi kira kira jam 23 perawat di ruang bayi memanggil sy utk menada tangani pemberian garamycin, katanya utk mencegah infeksi (bukan yg salep mata ya) krn jarak pecah ketuban ke kelahiran sdh 10 jam, jadi dikuatirkan nanti nanti tidak akan terjadi infeksi maka diberi garamycin. Sy meminta ditunda maksud hati mau browsing, tp sinyal bb tdk memungkinkan. Menurut saran mba, apakah sy menandatangani pemberian garamysin tsb atau tidak ya mba?
Terimakasih
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Thu Apr 18, 2013 6:57 pm (PDT) . Posted by:
"melessa" melessawijayachandra
Mbak,
Aku prnh ikut program bayi tabung dg dr aucky hinting..dan berhasil dpt kembar ce co skrg usia 5,5 yrs....dan diksh rejeki hamil alami oleh Tuhan ..jd sikmbr pny adik bayi 3,5 month...tny penerangan aja no tlp rs siloam...
Aku sdh lupa no tlpnya :p
Mel
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Aku prnh ikut program bayi tabung dg dr aucky hinting..dan berhasil dpt kembar ce co skrg usia 5,5 yrs....dan diksh rejeki hamil alami oleh Tuhan ..jd sikmbr pny adik bayi 3,5 month...tny penerangan aja no tlp rs siloam...
Aku sdh lupa no tlpnya :p
Mel
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Thu Apr 18, 2013 7:01 pm (PDT) . Posted by:
"asti kemala"
isoprinosine sudah saya tebus, jadi sempet saya minum beberapa hari.ok saya
stop
mengingat kehamilan pertama saya lemes bangeet dan ada riwayat preeklamsia,
jadi saya ikut aja dokternya
ok trimakasih buat temen temen infonya
Salam,
Asti
[Non-text portions of this message have been removed]
stop
mengingat kehamilan pertama saya lemes bangeet dan ada riwayat preeklamsia,
jadi saya ikut aja dokternya
ok trimakasih buat temen temen infonya
Salam,
Asti
[Non-text portions of this message have been removed]
Thu Apr 18, 2013 7:04 pm (PDT) . Posted by:
amianakbinus
Ini asti binus? (Wkwkwk kepedean)
Hehe ga ngikutin threadnya asti
Welcome yaaak di milist sehat -finally :) -
Isoprinosinnya nda usah ya sti, maem yg sehat2, positive thinking ajah :)
-ami
Sent from my BlackBerry® smartphone from Sinyal Bagus XL, Nyambung Teruuusss...!
Hehe ga ngikutin threadnya asti
Welcome yaaak di milist sehat -finally :) -
Isoprinosinnya nda usah ya sti, maem yg sehat2, positive thinking ajah :)
-ami
Sent from my BlackBerry® smartphone from Sinyal Bagus XL, Nyambung Teruuusss...
Thu Apr 18, 2013 7:48 pm (PDT) . Posted by:
"/Ghozan"
repost dari arsip milis th2006:
Mbak Ara,
Cuma mau kasih masukan dikit ttg isoprinosine, semoga bermanfaat ya.
Buat yang lain, maaf ya, agak panjang nih.
Ria
=================
Ria
dan Erna
Yang jelas gak ada negara yg pakai obat ini.
Kenapa kita mesti pakai?
wati
----- Original Message -----
From: "Riastuti, Trinovi" <Trinovi.Riastuti@pmintl.com >
Mbak Erna,
Pertanyaan ini jg pernah saya lontarkan ke prof Iwan, karena saya juga
mengkonsumsi selama kehamilan, dan anak saya jg sudah habis 2 botol
"obat"
ini. Selama ini memang dia sehat dan aktif. Berikut ini adalah jawaban
beliau. Jadi kesimpulan saya (semoga benar) isoporinosine sejauh ini
aman, namun tidak ada bukti efektifitasnya. Kalau tdk ada gunyanya,
buat apa dikonsumsi? Harganya kan jg nggak murah ya mbak? Hehehe..
Jadi kelak, saya akan coba mendiskusikan dg DSOG bila saya kembali
mendapatkan resep ini.
posted 09/06/2004 12:43:27
----------------------------------------------------------
Bukti yang negatif memang sulit dicari, ini tidak diumumkan oleh
Regulatory Authority, namun pernyataan saya adalah bukti dari Panitia
Obat Jadi
Sewaktu menilai obat itu. Bisa ditemukan di arsip kami.
Dampak negatif tidak diletahui, karena di pasaran negara lain barang
ini tidak muncul sebagai OBAT. Namun rupanya "cukup aman".
posted 09/06/2004 12:56:22
----------------------------------------------------------
--
Ini saya temukan bantahan dari FDA Amerika Serikat tentang keraguan
efektivitas Isoprinosine; (isoprinosine juga tidak dipasarkan di AS)
(1990):
Answers 06/21/1990
ISOPRINOSINE UPDATE
The June 21 issue of the New England Journal of Medicine reports a
randomized, placebo-controlled trial of inosine pranobex (isoprinosine),
an experimental immunomodulating agent. The study involved 866 persons
infected with HIV, the AIDS virus, in Sweden and Denmark. The report
suggests that patients in the isoprinosine arm of the trial were
significantly less likely to progress to AIDS than those patients in the
placebo arm of the trial. According to this report, during the 24-week
trial, 17 patients in the placebo arm progressed to AIDS as opposed to 2
patients in the isoprinosine arm.
Although the raw data from this study have not been submitted for review
to FDA by the drug's sponsor, Newport Pharmaceuticals Inc. of Laguna
Beach, Calif., the FDA's division of antiviral drug products has
reviewed the
report. The division prepared a response to the study report which also
appears in the same issue of the journal.
The division's response expresses a number of concerns about this study
and other studies conducted on isoprinosine, and states its belief that
more clinical investigation of this drug is needed before its value to
patients
can be well enough evaluated to decide whether, and on whom, it should
be
used.
-MORE-
Page 2, isoprinosine, T90-26
Isoprinosine has been under development as a treatment for HIV-infection
for approximately 5 years. Previous studies of isoprinosine's
effectiveness in delaying or preventing the onset of AIDS in
HIV-infected patients
conducted in the U.S. and other countries have not demonstrated that the
drug had any significant effect in slowing disease progression in
treated
patients.
For example, the company reported in November of 1988 that a multicenter
trial of the drug involving 696 HIV-infected patients in the U.S. and
the
U.K. showed no significant benefit in those treated with isoprinosine as
opposed to those given placebo. The sponsor is currently reanalyzing
data
from this study in order to evaluate why it produced a different result
than the Scandinavian trial.
There are also some issues concerning the design and analysis of this
latest Scandinavian study of isoprinosine. For example, the
classification
system for determining endpoints was changed during the course of the
study was one of a number of changes in the study's implementation and
analysis
that may have affected the study results, and may require additional,
balanced assessment. An editorial in the journal written by members of
FDA's division of anti-viral drug products also notes that the 24 weeks
of
the trial is a relatively short study period.
FDA believes that additional clinical testing should be conducted.
These could incorporate the use of pneumocystis prophylaxis and
retroviral
treatments that have recently been developed as standard therapies for
HIV-individuals, in order to determine how isoprinosine therapy, if
proven
effective, could be maximized in today's current therapeutic scene.
-----Original Message-----
From: Riastuti, Trinovi
Sent: Wednesday, June 09, 2004 12:02 PM
Dr Wati & smart parents,
Berikut jawaban dr prof Iwan ttg isoprinosine. Terima kasih untuk dr
Wati
atas sarannya. Bagaimana ya dok, supaya dongeng ini diketahui oleh para
dokter. Untuk skala kecil, mungkin kita bisa mulai dg DSA masing2 utk
membahas ini, semoga harapan kita untuk jadi bola salju (spt istilah dr
Wati) bisa terjadi. Amin...
Topic: Isoprinosine (SERU !)
Iwan D. posted 09/06/2004 11:08:14
----------------------------------------------------------
--
Isoprinosine tidak termasuk obat yg diakui di negara yg aturannya baik
sebagai anti-virus. Sekitar 15 tahun lalu obat ini dicoba utk
membuktikan
efektivitasnya di AS, namun tidak berhasil, dan setelah itu pabriknya
(yang hanya bikin obat ini) ditutup. Namun entah politik obat berjalan
terus dan
dipasarkan di negara berkembang. Indoneisa juga sudah menilai (oleh
Panitia Penilai Obat) dan dinyatakan "tidak ada bukti efektivitasnya";.
Farmako-politik berjalan terus dan POM menerima obat itu untuk
dipasarkan,
walaupun sudah diberitahu panitya bahwa tidak berguna. Itulah cerita
isoprinosine seperti intrik politik sekarang.
Hingga sekarang tidak ada bukti lanjut mengenai efektivitas
isoprinosine,
tapi dokter pakai terus. Itulah dongengnya yang tidak banyak diketahui
dokter.
-----Original Message-----
> From: wati [mailto:eji28896@indo.net.id ]
> Sent: Wednesday, June 09, 2004 7:50 AM
Ria
Sebenarnya sampai saat ini tak ada antivirus
Isoprinosin dulu diproduksi oleh a drug manufacturer in USA. Tapi sudah
tutup Coba kamu buka webnya Prof Iwandarmansjah
Bisa tanya beliau soal isoprinosin
Maaf, kalau pasien saya sih gak pernah dikasih isoprinosin dari dulu,
tapi
untuk omong saya rada susah soalnya terkait pembuat kebijakan
wati
-----Original Message-----
From: sehat@yahoogroups.com [mailto:sehat@yahoogroups.com ] On Behalf Of
qomaras
dan hasilnya.... :((
Tokso IGG+/ IGM -, ga maslah ya Dok..
Rubella IGG+85 DAN IGM+5. Hiks
Saya ga mengalami tanda2 khusus dari rubella ini, seperti panas, dan
ruam2..
semuanya berjalan seperti biasa.
OBAT : ACYCLOVIR dan ISOPRINOSINE 500
browsing di medicastore...ternyata effek obat yg disebut anti virus itu
banyak juga ya Dok..
apakah obat itu PERLU di minum Dok?
Mbak Ara,
Cuma mau kasih masukan dikit ttg isoprinosine, semoga bermanfaat ya.
Buat yang lain, maaf ya, agak panjang nih.
Ria
============
Ria
dan Erna
Yang jelas gak ada negara yg pakai obat ini.
Kenapa kita mesti pakai?
wati
----- Original Message -----
From: "Riastuti, Trinovi" <Trinovi.Riastuti@
Mbak Erna,
Pertanyaan ini jg pernah saya lontarkan ke prof Iwan, karena saya juga
mengkonsumsi selama kehamilan, dan anak saya jg sudah habis 2 botol
"obat"
ini. Selama ini memang dia sehat dan aktif. Berikut ini adalah jawaban
beliau. Jadi kesimpulan saya (semoga benar) isoporinosine sejauh ini
aman, namun tidak ada bukti efektifitasnya. Kalau tdk ada gunyanya,
buat apa dikonsumsi? Harganya kan jg nggak murah ya mbak? Hehehe..
Jadi kelak, saya akan coba mendiskusikan dg DSOG bila saya kembali
mendapatkan resep ini.
posted 09/06/2004 12:43:27
------------
Bukti yang negatif memang sulit dicari, ini tidak diumumkan oleh
Regulatory Authority, namun pernyataan saya adalah bukti dari Panitia
Obat Jadi
Sewaktu menilai obat itu. Bisa ditemukan di arsip kami.
Dampak negatif tidak diletahui, karena di pasaran negara lain barang
ini tidak muncul sebagai OBAT. Namun rupanya "cukup aman".
posted 09/06/2004 12:56:22
------------
--
Ini saya temukan bantahan dari FDA Amerika Serikat tentang keraguan
efektivitas Isoprinosine; (isoprinosine juga tidak dipasarkan di AS)
(1990):
Answers 06/21/1990
ISOPRINOSINE UPDATE
The June 21 issue of the New England Journal of Medicine reports a
randomized, placebo-controlled trial of inosine pranobex (isoprinosine)
an experimental immunomodulating agent. The study involved 866 persons
infected with HIV, the AIDS virus, in Sweden and Denmark. The report
suggests that patients in the isoprinosine arm of the trial were
significantly less likely to progress to AIDS than those patients in the
placebo arm of the trial. According to this report, during the 24-week
trial, 17 patients in the placebo arm progressed to AIDS as opposed to 2
patients in the isoprinosine arm.
Although the raw data from this study have not been submitted for review
to FDA by the drug's sponsor, Newport Pharmaceuticals Inc. of Laguna
Beach, Calif., the FDA's division of antiviral drug products has
reviewed the
report. The division prepared a response to the study report which also
appears in the same issue of the journal.
The division'
and other studies conducted on isoprinosine, and states its belief that
more clinical investigation of this drug is needed before its value to
patients
can be well enough evaluated to decide whether, and on whom, it should
be
used.
-MORE-
Page 2, isoprinosine, T90-26
Isoprinosine has been under development as a treatment for HIV-infection
for approximately 5 years. Previous studies of isoprinosine&#
effectiveness in delaying or preventing the onset of AIDS in
HIV-infected patients
conducted in the U.S. and other countries have not demonstrated that the
drug had any significant effect in slowing disease progression in
treated
patients.
For example, the company reported in November of 1988 that a multicenter
trial of the drug involving 696 HIV-infected patients in the U.S. and
the
U.K. showed no significant benefit in those treated with isoprinosine as
opposed to those given placebo. The sponsor is currently reanalyzing
data
from this study in order to evaluate why it produced a different result
than the Scandinavian trial.
There are also some issues concerning the design and analysis of this
latest Scandinavian study of isoprinosine. For example, the
classification
system for determining endpoints was changed during the course of the
study was one of a number of changes in the study's implementation and
analysis
that may have affected the study results, and may require additional,
balanced assessment. An editorial in the journal written by members of
FDA's division of anti-viral drug products also notes that the 24 weeks
of
the trial is a relatively short study period.
FDA believes that additional clinical testing should be conducted.
These could incorporate the use of pneumocystis prophylaxis and
retroviral
treatments that have recently been developed as standard therapies for
HIV-individuals, in order to determine how isoprinosine therapy, if
proven
effective, could be maximized in today's current therapeutic scene.
-----Original Message-----
From: Riastuti, Trinovi
Sent: Wednesday, June 09, 2004 12:02 PM
Dr Wati & smart parents,
Berikut jawaban dr prof Iwan ttg isoprinosine. Terima kasih untuk dr
Wati
atas sarannya. Bagaimana ya dok, supaya dongeng ini diketahui oleh para
dokter. Untuk skala kecil, mungkin kita bisa mulai dg DSA masing2 utk
membahas ini, semoga harapan kita untuk jadi bola salju (spt istilah dr
Wati) bisa terjadi. Amin...
Topic: Isoprinosine (SERU !)
Iwan D. posted 09/06/2004 11:08:14
------------
--
Isoprinosine tidak termasuk obat yg diakui di negara yg aturannya baik
sebagai anti-virus. Sekitar 15 tahun lalu obat ini dicoba utk
membuktikan
efektivitasnya di AS, namun tidak berhasil, dan setelah itu pabriknya
(yang hanya bikin obat ini) ditutup. Namun entah politik obat berjalan
terus dan
dipasarkan di negara berkembang. Indoneisa juga sudah menilai (oleh
Panitia Penilai Obat) dan dinyatakan "tidak ada bukti efektivitasnya"
Farmako-politik berjalan terus dan POM menerima obat itu untuk
dipasarkan,
walaupun sudah diberitahu panitya bahwa tidak berguna. Itulah cerita
isoprinosine seperti intrik politik sekarang.
Hingga sekarang tidak ada bukti lanjut mengenai efektivitas
isoprinosine,
tapi dokter pakai terus. Itulah dongengnya yang tidak banyak diketahui
dokter.
-----Original Message-----
> From: wati [mailto:eji28896@indo.
> Sent: Wednesday, June 09, 2004 7:50 AM
Ria
Sebenarnya sampai saat ini tak ada antivirus
Isoprinosin dulu diproduksi oleh a drug manufacturer in USA. Tapi sudah
tutup Coba kamu buka webnya Prof Iwandarmansjah
Bisa tanya beliau soal isoprinosin
Maaf, kalau pasien saya sih gak pernah dikasih isoprinosin dari dulu,
tapi
untuk omong saya rada susah soalnya terkait pembuat kebijakan
wati
-----Original Message-----
From: sehat@yahoogroups.
qomaras
dan hasilnya.... :((
Tokso IGG+/ IGM -, ga maslah ya Dok..
Rubella IGG+85 DAN IGM+5. Hiks
Saya ga mengalami tanda2 khusus dari rubella ini, seperti panas, dan
ruam2..
semuanya berjalan seperti biasa.
OBAT : ACYCLOVIR dan ISOPRINOSINE 500
browsing di medicastore.
banyak juga ya Dok..
apakah obat itu PERLU di minum Dok?
Thu Apr 18, 2013 7:29 pm (PDT) . Posted by:
"melessa" melessawijayachandra
Mbak,
Saya beli alat tensi merk om*on yg digital sekitar 600an di c*ntury...cara pemakaiannya gmpg..tinggal tekan tombol on off saja..
Bisa simpan 10 data
Mel
Powered by Telkomsel BlackBerry®
Saya beli alat tensi merk om*on yg digital sekitar 600an di c*ntury...cara pemakaiannya gmpg..tinggal tekan tombol on off saja..
Bisa simpan 10 data
Mel
Powered by Telkomsel BlackBerry®
Hati2 pakai yang digital, kalibrasinya gak jelas. Coba dengan 3 kali geser dikit posisi bisa berubah hasil. Cuma bisa buat indikasi kasar aja ya. Pengukuran duplo atau triplo lalu rata2. Hasil lebih akurat tetap yang air raksa, cuma mesti belajar caranya aja. Bisa tanya ke puskesmas buat belajar.
Rgds,
Marcella
*mpok bawel
Sent from my BlackBerry®
powered by Sinyal Kuat INDOSAT
Rgds,
Marcella
*mpok bawel
Sent from my BlackBerry®
powered by Sinyal Kuat INDOSAT
Thu Apr 18, 2013 7:40 pm (PDT) . Posted by:
"cheril mycat" ceril_cute
halo mb Imel.. di apotik banyak kok..:) wah baru sadar selama ini juga
masih mengikuti petunjuk di bungkusnya..musti banyak belajar lagi nih..
SOL
Sriyani
[Non-text portions of this message have been removed]
masih mengikuti petunjuk di bungkusnya..
SOL
Sriyani
[Non-text portions of this message have been removed]
Thu Apr 18, 2013 8:09 pm (PDT) . Posted by:
"Lovely Mom" lovelyvaresky
selamat pagi semua..
maaf bikin tulisan ini karna bingung mau nanya dimana & ke siapa.
sebenarnya ini masalah ibu yang usianya hampir 65th tapi ada riwayat darah tinggi,karna itulah tiap hari ibu slalu beli obat warung yang suka dia minum diam2. saya bingung harus berbuat aplg buat menghentikannya dikasih pengertian pelan sampe sy marah jg gak didengerin. sy cape...
sebenernya tiap bln sy slalu bw dia cek tekanan darah tingginya tetapi klo stabil dokter cm kasih amlodipine 5g 1x1 tapi itupun jarang dia minum malah dia minum obat warung jenis " rheumacyl & neuralgin " tiap hr selama ini mgkn udah hampir 4th ini.
dartingnya naik ato ngga dia slalu minum obat itu ,seperti ketergantungan.
sy sering kali selalu menganjurkan hidup sehat, byk mkn syr dan buah dan jgn slalu tergantung sm obt aplg obt warung tp susah.. (ibu tggl bersama kami) entahlah hrs gmn lg pdhl sy slalu blg sm dia kasihan ginjal klo terus2an dikasih obt kimia sprt itu.
semua obt ada efeknya aplg sampe bertahun2 dan jangka panjang. tkt nanti ginjal ruksak ato gmn tp tetep...
saya hrs gmn ya semua? sy bingung.. sy cape.. dia suka beli obt itu diam2 sampe stok byk.
maaf jd kepanjangan curhatnya.
thanks ya..
Sent from my iPhone
maaf bikin tulisan ini karna bingung mau nanya dimana & ke siapa.
sebenarnya ini masalah ibu yang usianya hampir 65th tapi ada riwayat darah tinggi,karna itulah tiap hari ibu slalu beli obat warung yang suka dia minum diam2. saya bingung harus berbuat aplg buat menghentikannya dikasih pengertian pelan sampe sy marah jg gak didengerin. sy cape...
sebenernya tiap bln sy slalu bw dia cek tekanan darah tingginya tetapi klo stabil dokter cm kasih amlodipine 5g 1x1 tapi itupun jarang dia minum malah dia minum obat warung jenis " rheumacyl & neuralgin " tiap hr selama ini mgkn udah hampir 4th ini.
dartingnya naik ato ngga dia slalu minum obat itu ,seperti ketergantungan.
sy sering kali selalu menganjurkan hidup sehat, byk mkn syr dan buah dan jgn slalu tergantung sm obt aplg obt warung tp susah.. (ibu tggl bersama kami) entahlah hrs gmn lg pdhl sy slalu blg sm dia kasihan ginjal klo terus2an dikasih obt kimia sprt itu.
semua obt ada efeknya aplg sampe bertahun2 dan jangka panjang. tkt nanti ginjal ruksak ato gmn tp tetep...
saya hrs gmn ya semua? sy bingung.. sy cape.. dia suka beli obt itu diam2 sampe stok byk.
maaf jd kepanjangan curhatnya.
thanks ya..
Sent from my iPhone
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Terima kasih & penghargaan sedalam-dalamnya kepada : HBTLaw, PT.Intiland, dan PT. Permata Bank Tbk. yang telah dan konsisten mensponsori program kami, PESAT (Program Edukasi Kesehatan Anak Untuk Orang Tua)."
"Milis SEHAT didukung oleh : CBN Net Internet Access &Website.
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Milis Sehat thanks to:
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Our biggest gratitude to: HBTLaw, PT. Intiland, and PT. Permata Bank Tbk. who have consistently sponsored our program, PESAT (Program Edukasi Kesehatan Anak Untuk Orang Tua)."
"SEHAT mailing list is supported by CBN Net for Internet Access &Website.
Kunjungi kami di (Visit us at):
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